Miriam O'Callaghan will be standing in for Ryan Tubridy on tonight's Late Late Show.
RTÉ confirmed that due to a persistent cough, Tubridy is adhering to best practice and staying away from the show.
It makes the first time that a woman will present the world's longest running TV chat show.
"I'm delighted to be able to step in tonight and present the Late Late Show. We have to keep the show on the road. Best wishes to Ryan," Miriam said.
The Late Late Show will be paying tribute to the men and women of Ireland's National Frontline Services tonight.
In what promises to be a very special opening segment for the show, the Late Late will pay tribute to those who have been bravely leading the fight to slow down and treat the spread of Coronavirus.
Viewers around the country will then be invited to join in a collective round of applause for our frontline service heroes.
Global superstar Hozier will launch an emergency on-air appeal for the ISPCC who are experiencing an upsurge in calls to Childline.
He will perform an exclusive set, live in studio, and promote a new initiative between ISPCC and RTÉ 2FM, where top Irish artists are performing across 2FM every night for a fortnight to raise funds.
Caroline O'Sullivan from the ISPCC will be on The Late Late Show with helpful advice for parents who are dealing with children affected by the current situation.
Lee Duffy, a young, fit and healthy League of Ireland footballer, will talk about about his harrowing experience when he contracted Coronavirus and was hospitalised. Luckily, Lee has now made a full recovery and will be in studio to issue a plea to the young people of Ireland to heed warnings regarding social gatherings.
Mrs Brown's Boys stars Brendan O'Carroll and wife Jennifer Gibney will be talking via Skype link from Florida, and comedian Dara Ó Briain will join the show from London.
Former Irish Rugby International Brian O'Driscoll will also be on tomorrow's show, as well as legendary GAA commentator Mícheál Ó Muircheartaigh.
Photo via RTÉ. 
