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3rd August 2018
02:09pm BST

"In pregnancy and childbirth, the sex of the baby is at the forefront of many parents' minds, but we do not even think of the placenta as having a sex. This work shows that the placenta differs profoundly according to sex."In a female placenta, the spermine-producing enzymes were much higher than in a male-placenta, leading to a higher level of spermine in the mother's blood. The male placenta, on the other hand, was found to be more susceptible to the toxic effects of a drug that blocked spermine production.
The research also showed that the amount of spermine in a mother's blood affects the risk of pre-eclampsia.
Mums are put at an increased risk of pre-eclampsia with higher levels of spermine, while baby boys are more at risk than girls of restricted growth because of the lower levels of spermine.
This is in line with previous research that shows that mothers of girls are more at risk of pre-eclampsia and that boys are more at risk of foetal growth restriction.
Smith discusses the significance of these findings:
"Better understanding of these differences could lead to new predictive tests and possibly even new approaches to reducing the risk of poor pregnancy outcome."Parents who don't want to know the sex of the baby need not worry, though, because you can be sure that your doctor is taking note.