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Pregnancy

20th Sep 2019

New study finds babies born by C-section lack healthy gut bacteria from mother

Trine Jensen-Burke

babies born by C-section

Over the past couple of years, medical experts have dedicated a lot of attention and research hours to gut bacteria, and just how incredibly important our microbiome is to our overall health and wellbeing.

Gut bacteria can be affected by many factors, such as our diet, drugs we take (particularly antibiotics), other health conditions we might have, and many more variables.

And now, researchers have discovered that the gut bacteria in babies can even be affected by delivery method.

According to a new UK-based study, scientists discovered that infants born via Caesarean section were lacking much of the health-associated bacteria from their mothers than babies born naturally through vaginal delivery.

Instead, the babies born by C-section had more bacteria associated with hospital environments in their guts.

babies born by C-section

The Baby Biome study, conducted by researchers from the Wellcome Sanger Institute, UCL, the University of Birmingham and their collaborators, stressed that the exact role of the baby’s gut bacteria remains unclear, and that it is yet unknown whether or not these differences at birth will have any long-term consequences.

Carrying our their research, the UK scientists examined 1,679 samples of gut bacteria from 596 babies and 175 mothers for the study, which was published in Nature. Faecal samples were taken from babies aged four days, seven days or 21 days, after they were delivered in UK hospitals naturally or by Caesarean.

Maybe unsurprisingly when you consider the way they come into the world, the study found that babies delivered naturally had many more health-associated bacteria from their mothers than babies who were born by Caesarean.

Here is what Dr Nigel Field, clinical associate professor at UCL, had to say about the research:

“Babies are sterile when they are in the womb,” Field explains. “And the moment they are born is the moment when the immune system has a huge number of bacteria that is it presented with. And so the hypothesis is that the moment of birth might be a sort of thermostat moment which sets the immune system for future life.”

Possibly due to this difference in gut bacteria, the study showed that babies born by C-section have a slightly higher risk of immune-related conditions, explains Field. They also have a slightly higher risk of asthma, inflammatory bowel disease and other allergic conditions.

“The first weeks of life are a critical window of development of the baby’s immune system, but we know very little about it,” Professor Peter Brocklehurst of the University of Birmingham, who led the study, said to Sky News.

“We urgently need to follow up this study, looking at these babies as they grow to see if early differences in the microbiome lead to any health issues.”

However, and this is good news – research also shows that the differences in gut bacteria between naturally born and Caesarean delivered babies largely evened out one year after birth, and experts agree that much more research in this area is needed.